Description :

Dissolved carbon dioxide (CO2) is a well‐known critical parameter in bioprocesses due to its significant impact on cell metabolism and on product quality attributes. Processes run at small‐scale faces many challenges due to limited options for modular sensors for online monitoring and control. Traditional sensors are bulky, costly, and invasive in nature and do not fit in small‐scale systems. In this study, we present the implementation of a novel, rate‐based technique for on-field measurement of CO2 in bioprocesses. The gas inside the probe was then allowed to recirculate through gas‐impermeable
tubing to a DCD25 meter.